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Description:
AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fold more selective for PI3Kγ than PI3Kδ/β and PI3Kα in cell-free assays, respectively.
Chemical Information:
Molecular Weight (MW) 257.27 Formula
C12H7N3O2S
CAS No. 648450-29-7 Solubility (25°C) * DMSO 0.4 mg/mL (1.55 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
PI3Kδ PI3Kβ PI3Kγ 0.5 μM 75 μM 29 μM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.8870 mL 19.4348 mL 38.8697 mL 5 mM 0.7774 mL 3.8870 mL 7.7739 mL 10 mM 0.3887 mL 1.9435 mL 3.8870 mL 50 mM 0.0777 mL 0.3887 mL 0.7774 mL
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