Rho inhibitor_Cell Cycle_Chem Catch, Global Inhibitor Store

Home About Us Newest Recommend

Search

Search Type： Product Name, Cat No., CAS No., Chemical Name

Your Position: Home > Cell Cycle > Rho inhibitor

All Categories

Angiogenesis

Apoptosis

Autophagy

Cell Cycle

Cytoskeletal Signaling

DNA Damage

Endocrinology & Hormones

Epigenetics

GPCR & G Protein

Immunology & Inflammation

JAK/STAT

kit

MAPK

Metabolism

Microbiology

Neuronal Signaling

NF-κB

Others

PI3K/Akt/mTOR

Proteases

Protein Tyrosine Kinase

Stem Cells & Wnt

TGF-beta/Smad

Transmembrane Transporters

Ubiquitin

Goods List

Cat#

Goods Name

description

Zoledronic Acid

Zoledronic acid (ZA), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho.

ZCL278 is a selective Cdc42 GTPase inhibitor with K_d of 11.4 μM.

Salirasib is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with K_i of 2.6 μM, which inhibits _Ras methylation. Phase 2.

NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA.

ML141 (CID-2950007), is demonstrated to be a potent, selective and reversible non-competitive inhibitor of Cdc42 GTPase suitable for in vitro assays, with IC50 of 200 nM and selectivity against other members of the Rho family of GTPases (Rac

Kobe0065 is H-Ras-cRaf1 interaction inhibitor, exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.

K-Ras(G12C) inhibitor 9

K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).

6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C).

EHT 1864 2HCl is a potent Rac family GTPase inhibitor with K_d of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively.

EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-435 and MDA-MB-231 cells, equally potent inhibition for Rac3.

Chem Catch products are for research use only. Not for human use. We do not sell to patients.

沪ICP备16042327号-2