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K-Ras(G12C) inhibitor 9

K-Ras(G12C) inhibitor 9

Catalog Number: CC7488 Rank: comment rank 5

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Description:

K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).

Chemical Information:

Molecular Weight (MW) 513.78
Formula

 

C16H21ClIN3O4

 

CAS No. 1469337-91-4
Solubility (25°C) * DMSO 53 mg/mL (103.15 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
P-glycoprotein
5.1 nM (Kd)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9464 mL 9.7318 mL 19.4636 mL
5 mM 0.3893 mL 1.9464 mL 3.8927 mL
10 mM 0.1946 mL 0.9732 mL 1.9464 mL
50 mM 0.0389 mL 0.1946 mL 0.3893 mL


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