Description：

AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ in cell-free assays. Phase 1.

Chemical Information：

Molecular Weight (MW)		408.45
Formula		C22H24N4O4
CAS No.		1173900-33-8
Solubility (25°C) *	DMSO	82 mg/mL (200.75 mM)
	Water	Insoluble
	Alcohol	10 mg/mL (24.48 mM)

Biological Activity：

Targets IC50

HDAC3 HDAC5 HDAC4 HDAC9 HDAC10 HDAC1 43 nM 47 nM 56 nM 70 nM 40 nM 49 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4483 mL	12.2414 mL	24.4828 mL
5 mM	0.4897 mL	2.4483 mL	4.8966 mL
10 mM	0.2448 mL	1.2241 mL	2.4483 mL
50 mM	0.0490 mL	0.2448 mL	0.4897 mL

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