Description：

CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases.

Chemical Information：

Molecular Weight (MW)		437.53
Formula		C25H31N3O4
CAS No.		1802175-06-9
Solubility (25°C) *	DMSO	20 mg/mL warmed (45.71 mM)
	Water	Insoluble
	Alcohol	18 mg/mL warmed (41.14 mM)

Biological Activity：

Targets IC50

JAK2 1.8 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2856 mL	11.4278 mL	22.8556 mL
5 mM	0.4571 mL	2.2856 mL	4.5711 mL
10 mM	0.2286 mL	1.1428 mL	2.2856 mL
50 mM	0.0457 mL	0.2286 mL	0.4571 mL

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