Description：

CPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.

Chemical Information：

Molecular Weight (MW)		528.66
Formula		C27H36N4O5S
CAS No.		1450655-76-1
Solubility (25°C) *	DMSO	100 mg/mL (189.15 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (189.15 mM)

Biological Activity：

Targets IC50

SIRT1 SIRT2 131 μM 38 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8916 mL	9.4579 mL	18.9157 mL
5 mM	0.3783 mL	1.8916 mL	3.7831 mL
10 mM	0.1892 mL	0.9458 mL	1.8916 mL
50 mM	0.0378 mL	0.1892 mL	0.3783 mL

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