Description：

Copanlisib (BAY 80-6946) is a potent pan-class I PI3K with IC50 of 0.5, 3.7, 6.4, and 0.7 nM in cell-free assays for PI3Kα/β/γ/δ , respectively. Phase 3.

Chemical Information：

Molecular Weight (MW)		480.52
Formula		C23H28N8O4
CAS No.		1032568-63-0
Solubility (25°C) *	DMSO	0.002 mg/mL (0.0 mM)
	Water
	Alcohol	0.01 mg/mL (0.02 mM)

Biological Activity：

Targets IC50

c-MET 0.13 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0811 mL	10.4054 mL	20.8108 mL
5 mM	0.4162 mL	2.0811 mL	4.1622 mL
10 mM	0.2081 mL	1.0405 mL	2.0811 mL
50 mM	0.0416 mL	0.2081 mL	0.4162 mL

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