Description：

CZC24832 is the first selective PI3Kγ inhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ.

Chemical Information：

Molecular Weight (MW)		364.4
Formula		C15H17FN6O2S
CAS No.		1159824-67-5
Solubility (25°C) *	DMSO	5 mg/mL warmed (13.72 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

TNF-α NOD2 NOD1 > 20 μM > 20 μM 0.56 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7442 mL	13.7212 mL	27.4424 mL
5 mM	0.5488 mL	2.7442 mL	5.4885 mL
10 mM	0.2744 mL	1.3721 mL	2.7442 mL
50 mM	0.0549 mL	0.2744 mL	0.5488 mL

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