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Search Type: Product Name, Cat No., CAS No., Chemical Name
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Description:
CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2.
Chemical Information:
Molecular Weight (MW) 501.8 Formula
C22H18Cl2N8.HCl
CAS No. 1797989-42-4 Solubility (25°C) * DMSO 93 mg/mL (185.33 mM) Water Insoluble Alcohol 2 mg/mL (3.98 mM)
Biological Activity:
Targets IC50
5-HT 0.95 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9928 mL 9.9641 mL 19.9283 mL 5 mM 0.3986 mL 1.9928 mL 3.9857 mL 10 mM 0.1993 mL 0.9964 mL 1.9928 mL 50 mM 0.0399 mL 0.1993 mL 0.3986 mL
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