Description：

Capmatinib (INCB28060) is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Phase 1.

Chemical Information：

Molecular Weight (MW)		412.42
Formula		C23H17FN6O
CAS No.		1029712-80-8
Solubility (25°C) *	DMSO	2 mg/mL (4.84 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4247 mL	12.1236 mL	24.2471 mL
5 mM	0.4849 mL	2.4247 mL	4.8494 mL
10 mM	0.2425 mL	1.2124 mL	2.4247 mL
50 mM	0.0485 mL	0.2425 mL	0.4849 mL

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