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Description:
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM, also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. Phase 1.
Chemical Information:
Molecular Weight (MW) 468.84 Formula
C23H15ClF2N4O3
CAS No. 1174046-72-0 Solubility (25°C) * DMSO 94 mg/mL (200.49 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
procollagen C-pr 44 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.1329 mL 10.6646 mL 21.3292 mL 5 mM 0.4266 mL 2.1329 mL 4.2658 mL 10 mM 0.2133 mL 1.0665 mL 2.1329 mL 50 mM 0.0427 mL 0.2133 mL 0.4266 mL
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