Description：

BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. Also inhibiting components of the ubiquitin system.

Chemical Information：

Molecular Weight (MW)		207.25
Formula		C10H9NO2S
CAS No.		19542-67-7
Solubility (25°C) *	DMSO	41 mg/mL (197.82 mM)
	Water	Insoluble
	Alcohol	10 mg/mL (48.25 mM)

Biological Activity：

Targets IC50

PKA S6K1 48 nM (Ki) 80 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	4.8251 mL	24.1255 mL	48.2509 mL
5 mM	0.9650 mL	4.8251 mL	9.6502 mL
10 mM	0.4825 mL	2.4125 mL	4.8251 mL
50 mM	0.0965 mL	0.4825 mL	0.9650 mL

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