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Description:
Bardoxolone Methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor.
Chemical Information:
Molecular Weight (MW) 505.69 Formula
C32H43NO4
CAS No. 218600-53-4 Solubility (25°C) * DMSO 21 mg/mL (41.52 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
Aβ40 γ secretase ICN 14 nM 4 nM 5 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9775 mL 9.8875 mL 19.7750 mL 5 mM 0.3955 mL 1.9775 mL 3.9550 mL 10 mM 0.1977 mL 0.9887 mL 1.9775 mL 50 mM 0.0395 mL 0.1977 mL 0.3955 mL
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