Description：

AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor with pKi of 8.3 for BRD4.

Chemical Information：

Molecular Weight (MW)		667.75
Formula		C25H33N7O3.C11H8O3
CAS No.		1869912-40-2
Solubility (25°C) *	DMSO	100 mg/mL (149.75 mM)
	Water	Insoluble
	Alcohol	27 mg/mL warmed (40.43 mM)

Biological Activity：

Targets IC50

Inosine monophos Inosine monopho 27 nM 39 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.4976 mL	7.4878 mL	14.9757 mL
5 mM	0.2995 mL	1.4976 mL	2.9951 mL
10 mM	0.1498 mL	0.7488 mL	1.4976 mL
50 mM	0.0300 mL	0.1498 mL	0.2995 mL

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