Description：

RO4929097 is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.

Chemical Information：

Molecular Weight (MW)		469.4
Formula		C22H20F5N3O3
CAS No.		847925-91-1
Solubility (25°C) *	DMSO	93 mg/mL (198.12 mM)
	Water	Insoluble
	Alcohol	16 mg/mL (34.08 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1304 mL	10.6519 mL	21.3038 mL
5 mM	0.4261 mL	2.1304 mL	4.2608 mL
10 mM	0.2130 mL	1.0652 mL	2.1304 mL
50 mM	0.0426 mL	0.2130 mL	0.4261 mL

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