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Description:
(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
Chemical Information:
Molecular Weight (MW) 331.81 Formula
C14H15F2N3S.HCl
CAS No. 195881-94-8 Solubility (25°C) * DMSO 66 mg/mL (198.9 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.0138 mL 15.0689 mL 30.1377 mL 5 mM 0.6028 mL 3.0138 mL 6.0275 mL 10 mM 0.3014 mL 1.5069 mL 3.0138 mL 50 mM 0.0603 mL 0.3014 mL 0.6028 mL
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