Description：

Nepicastat (SYN-117) HCl is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. Phase 2.

Chemical Information：

Molecular Weight (MW)		331.81
Formula		C14H15F2N3S.HCl
CAS No.		170151-24-3
Solubility (25°C) *	DMSO	66 mg/mL (198.9 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.0138 mL	15.0689 mL	30.1377 mL
5 mM	0.6028 mL	3.0138 mL	6.0275 mL
10 mM	0.3014 mL	1.5069 mL	3.0138 mL
50 mM	0.0603 mL	0.3014 mL	0.6028 mL

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