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Palbociclib (PD0332991) Isethionate

Palbociclib (PD0332991) Isethionate

Catalog Number: CC1735 Rank: comment rank 5

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Description:

Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.

Chemical Information:

Molecular Weight (MW) 573.66
Formula

 

C24H29N7O2.C2H6O4S

 

CAS No. 827022-33-3
Solubility (25°C) * DMSO Insoluble
Water 10 mg/mL warmed (17.43 mM)
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.7432 mL 8.7160 mL 17.4319 mL
5 mM 0.3486 mL 1.7432 mL 3.4864 mL
10 mM 0.1743 mL 0.8716 mL 1.7432 mL
50 mM 0.0349 mL 0.1743 mL 0.3486 mL


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