Description：

K03861 is a type II CDK2 inhibitor with K_d of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

Chemical Information：

Molecular Weight (MW)		501.50
Formula		C24H26F3N7O2
CAS No.		853299-07-7
Solubility (25°C) *	DMSO	100 mg/mL (199.4 mM)
	Water	Insoluble
	Alcohol	15 mg/mL (29.91 mM)

Biological Activity：

Targets IC50

CXCL12-mediated CXCR4 5.7 nM 44 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9940 mL	9.9701 mL	19.9402 mL
5 mM	0.3988 mL	1.9940 mL	3.9880 mL
10 mM	0.1994 mL	0.9970 mL	1.9940 mL
50 mM	0.0399 mL	0.1994 mL	0.3988 mL

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