Description：

Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.

Chemical Information：

Molecular Weight (MW)		425.50
Formula		C21H23N5O3S
CAS No.		1206161-97-8
Solubility (25°C) *	DMSO	85 mg/mL (199.76 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3502 mL	11.7509 mL	23.5018 mL
5 mM	0.4700 mL	2.3502 mL	4.7004 mL
10 mM	0.2350 mL	1.1751 mL	2.3502 mL
50 mM	0.0470 mL	0.2350 mL	0.4700 mL

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