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EPZ015666(GSK3235025)

EPZ015666(GSK3235025)

Catalog Number: CC7904 Rank: comment rank 5

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Description:

EPZ015666(GSK3235025) is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs.

Chemical Information:

Molecular Weight (MW) 383.44
Formula

 

C20H25N5O3

 

CAS No. 1616391-65-1
Solubility (25°C) * DMSO 60 mg/mL warmed (156.47 mM)
Water Insoluble
Alcohol 48 mg/mL warmed (125.18 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.6080 mL 13.0398 mL 26.0797 mL
5 mM 0.5216 mL 2.6080 mL 5.2159 mL
10 mM 0.2608 mL 1.3040 mL 2.6080 mL
50 mM 0.0522 mL 0.2608 mL 0.5216 mL


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