Description：

EPZ005687 is a potent and selective inhibitor of EZH2 with K_i of 24 nM in a cell-free assay, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.

Chemical Information：

Molecular Weight (MW)		539.67
Formula		C32H37N5O3
CAS No.		1396772-26-1
Solubility (25°C) *	DMSO	2 mg/mL (3.7 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8530 mL	9.2649 mL	18.5298 mL
5 mM	0.3706 mL	1.8530 mL	3.7060 mL
10 mM	0.1853 mL	0.9265 mL	1.8530 mL
50 mM	0.0371 mL	0.1853 mL	0.3706 mL

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