Description：

EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM in a cell-free assay and demonstrates >1,200-fold selectivity for DOT1L over all other tested PMTs.

Chemical Information：

Molecular Weight (MW)		539.67
Formula		C28H41N7O4
CAS No.		1338466-77-5
Solubility (25°C) *	DMSO	100 mg/mL (185.29 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (185.29 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8530 mL	9.2649 mL	18.5298 mL
5 mM	0.3706 mL	1.8530 mL	3.7060 mL
10 mM	0.1853 mL	0.9265 mL	1.8530 mL
50 mM	0.0371 mL	0.1853 mL	0.3706 mL

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