Description：

ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.

Chemical Information：

Molecular Weight (MW)		525.56
Formula		C25H31N7O6
CAS No.		1291074-87-7
Solubility (25°C) *	DMSO	100 mg/mL warmed(190.27 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

β-lactamase 33 mM (Kd)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9027 mL	9.5137 mL	19.0273 mL
5 mM	0.3805 mL	1.9027 mL	3.8055 mL
10 mM	0.1903 mL	0.9514 mL	1.9027 mL
50 mM	0.0381 mL	0.1903 mL	0.3805 mL

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