Description：

Enasidenib (AG-221) is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzyme with IC50 of 12 nM.

Chemical Information：

Molecular Weight (MW)		473.38
Formula		C19H17F6N7O
CAS No.		1446502-11-9
Solubility (25°C) *	DMSO	94 mg/mL (198.57 mM)
	Water	Insoluble
	Alcohol	94 mg/mL (198.57 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1125 mL	10.5623 mL	21.1247 mL
5 mM	0.4225 mL	2.1125 mL	4.2249 mL
10 mM	0.2112 mL	1.0562 mL	2.1125 mL
50 mM	0.0422 mL	0.2112 mL	0.4225 mL

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