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Empagliflozin (BI 10773)

Empagliflozin (BI 10773)

Catalog Number: CC8178 Rank: comment rank 5

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Description:

Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.

Chemical Information:

Molecular Weight (MW) 450.91
Formula

 

C23H27ClO7

 

CAS No. 864070-44-0
Solubility (25°C) * DMSO 90 mg/mL (199.59 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
M2 M4 M5 M3 M1
0.14 nM 0.21 nM 0.16 nM 0.14 nM 0.1 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.2177 mL 11.0887 mL 22.1774 mL
5 mM 0.4435 mL 2.2177 mL 4.4355 mL
10 mM 0.2218 mL 1.1089 mL 2.2177 mL
50 mM 0.0444 mL 0.2218 mL 0.4435 mL


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