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Description:
Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.
Chemical Information:
Molecular Weight (MW) 450.91 Formula
C23H27ClO7
CAS No. 864070-44-0 Solubility (25°C) * DMSO 90 mg/mL (199.59 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
M2 M4 M5 M3 M1 0.14 nM 0.21 nM 0.16 nM 0.14 nM 0.1 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.2177 mL 11.0887 mL 22.1774 mL 5 mM 0.4435 mL 2.2177 mL 4.4355 mL 10 mM 0.2218 mL 1.1089 mL 2.2177 mL 50 mM 0.0444 mL 0.2218 mL 0.4435 mL
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