Description：

E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.

Chemical Information：

Molecular Weight (MW)		378.46
Formula		C21H30O6
CAS No.		136164-66-4
Solubility (25°C) *	DMSO	75 mg/mL (198.17 mM)
	Water	Insoluble
	Alcohol	75 mg/mL (198.17 mM)

Biological Activity：

Targets IC50

FXR VDR DNA Polymerase PXR 3.8 μM (EC50) [ 29μM (Ki) 15μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6423 mL	13.2114 mL	26.4229 mL
5 mM	0.5285 mL	2.6423 mL	5.2846 mL
10 mM	0.2642 mL	1.3211 mL	2.6423 mL
50 mM	0.0528 mL	0.2642 mL	0.5285 mL

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