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Description:
E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM.
Chemical Information:
Molecular Weight (MW) 357.41 Formula
C15H27N5O5
CAS No. 66701-25-5 Solubility (25°C) * DMSO 71 mg/mL warmed (198.65 mM) Water 11 mg/mL warmed (30.77 mM) Alcohol Insoluble
Biological Activity:
Targets IC50
DPP-4 19 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.7979 mL 13.9895 mL 27.9791 mL 5 mM 0.5596 mL 2.7979 mL 5.5958 mL 10 mM 0.2798 mL 1.3990 mL 2.7979 mL 50 mM 0.0560 mL 0.2798 mL 0.5596 mL
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