Description：

Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with K_i and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases. Phase 3.

Chemical Information：

Molecular Weight (MW)		416.86
Formula		C22H17ClN6O
CAS No.		1201438-56-3
Solubility (25°C) *	DMSO	83 mg/mL(199.1 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Opioid 58 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3989 mL	11.9944 mL	23.9889 mL
5 mM	0.4798 mL	2.3989 mL	4.7978 mL
10 mM	0.2399 mL	1.1994 mL	2.3989 mL
50 mM	0.0480 mL	0.2399 mL	0.4798 mL

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