Description：

Duloxetine HCl is a serotonin-norepinephrine reuptake inhibitor with K_i of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).

Chemical Information：

Molecular Weight (MW)		333.88
Formula		C18H19NOS.HCl
CAS No.		136434-34-9
Solubility (25°C) *	DMSO	67 mg/mL (200.67 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Dopamine D2 1.1 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.9951 mL	14.9754 mL	29.9509 mL
5 mM	0.5990 mL	2.9951 mL	5.9902 mL
10 mM	0.2995 mL	1.4975 mL	2.9951 mL
50 mM	0.0599 mL	0.2995 mL	0.5990 mL

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