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Description:
Doxorubicin (Adriamycin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis in tumor cells.
Chemical Information:
Molecular Weight (MW) 579.98 Formula
C27H29NO11.HCl
CAS No. 25316-40-9 Solubility (25°C) * DMSO 100 mg/mL warmed (172.41 mM) Water 20 mg/mL (34.48 mM) Alcohol Insoluble
Biological Activity:
Targets IC50
Sigma 1 receptor 5-HT2 Norepinephrine Serotonin recep 5-HT4 287 nM 235 nM 13.3 nM 3.45 nM 7.31 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.7242 mL 8.6210 mL 17.2420 mL 5 mM 0.3448 mL 1.7242 mL 3.4484 mL 10 mM 0.1724 mL 0.8621 mL 1.7242 mL 50 mM 0.0345 mL 0.1724 mL 0.3448 mL
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