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Doxapram HCl

Doxapram HCl

Catalog Number: CC4193 Rank: comment rank 5

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Description:

Doxapram HCl inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.

Chemical Information:

Molecular Weight (MW) 432.98
Formula

 

C24H30N2O2.HCl.H2O

 

CAS No. 7081-53-0
Solubility (25°C) * DMSO 87 mg/mL (200.93 mM)
Water 25 mg/mL (57.73 mM)
Alcohol 2 mg/mL (4.61 mM)


Biological Activity:

Targets
IC50
Histamine H3
1.9 μM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3096 mL 11.5479 mL 23.0958 mL
5 mM 0.4619 mL 2.3096 mL 4.6192 mL
10 mM 0.2310 mL 1.1548 mL 2.3096 mL
50 mM 0.0462 mL 0.2310 mL 0.4619 mL


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