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Description:
Dorsomorphin 2HCl is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Also inhibits type Ⅰ BMP receptor activity.
Chemical Information:
Molecular Weight (MW) 472.41 Formula
C24H25N5O.2HCl
CAS No. 1219168-18-9 Solubility (25°C) * DMSO Insoluble Water 94 mg/mL (198.97 mM) Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.1168 mL 10.5840 mL 21.1681 mL 5 mM 0.4234 mL 2.1168 mL 4.2336 mL 10 mM 0.2117 mL 1.0584 mL 2.1168 mL 50 mM 0.0423 mL 0.2117 mL 0.4234 mL
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