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Description:
Dorsomorphin is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Also inhibits type I BMP receptor activity.
Chemical Information:
Molecular Weight (MW) 399.49 Formula
C24H25N5O
CAS No. 866405-64-3 Solubility (25°C) * DMSO 3 mg/mL warmed (7.5 mM) Water Insoluble Alcohol 2 mg/mL warmed (5.0 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.5032 mL 12.5160 mL 25.0319 mL 5 mM 0.5006 mL 2.5032 mL 5.0064 mL 10 mM 0.2503 mL 1.2516 mL 2.5032 mL 50 mM 0.0501 mL 0.2503 mL 0.5006 mL
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