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Description:
DMXAA (Vadimezan) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. Phase 3.
Chemical Information:
Molecular Weight (MW) 282.29 Formula
C17H14O4
CAS No. 117570-53-3 Solubility (25°C) * DMSO 7 mg/mL (24.79 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
H1 30 μM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.5425 mL 17.7123 mL 35.4246 mL 5 mM 0.7085 mL 3.5425 mL 7.0849 mL 10 mM 0.3542 mL 1.7712 mL 3.5425 mL 50 mM 0.0708 mL 0.3542 mL 0.7085 mL
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