Description：

Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions. Diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.

Chemical Information：

Molecular Weight (MW)		369.29
Formula		C14H11Cl2NO2.C4H11N
CAS No.		78213-16-8
Solubility (25°C) *	DMSO	74 mg/mL (200.38 mM)
	Water	Insoluble
	Alcohol	74 mg/mL (200.38 mM)

Biological Activity：

Targets IC50

α2-adrenoceptor 1.08 nM (Ki )

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7079 mL	13.5395 mL	27.0790 mL
5 mM	0.5416 mL	2.7079 mL	5.4158 mL
10 mM	0.2708 mL	1.3539 mL	2.7079 mL
50 mM	0.0542 mL	0.2708 mL	0.5416 mL

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