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Description:
Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.
Chemical Information:
Molecular Weight (MW) 307.39 Formula
C19H21N3O
CAS No. 147084-10-4 Solubility (25°C) * DMSO 28 mg/mL (91.08 mM) Water Insoluble Alcohol 61 mg/mL (198.44 mM)
Biological Activity:
Targets IC50
Aurora A Aurora B 110 nM 130 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.2532 mL 16.2660 mL 32.5320 mL 5 mM 0.6506 mL 3.2532 mL 6.5064 mL 10 mM 0.3253 mL 1.6266 mL 3.2532 mL 50 mM 0.0651 mL 0.3253 mL 0.6506 mL
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