Description：

DAPTA is a water soluble potent, selective CCR5 antagonist which potently inhibits specific CD4-dependent binding of gp120 Bal (IC50 = 0.06 nM) and CM235 (IC50 = 0.32 nM) to CCR5.

Chemical Information：

Molecular Weight (MW)		856.88
Formula		C35H56N10O15
CAS No.		106362-34-9
Solubility (25°C) *	DMSO
	Water	100 mg/mL (116.7 mM)
	Alcohol

Biological Activity：

Targets IC50

HIV reverse tran 24 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.1670 mL	5.8351 mL	11.6702 mL
5 mM	0.2334 mL	1.1670 mL	2.3340 mL
10 mM	0.1167 mL	0.5835 mL	1.1670 mL
50 mM	0.0233 mL	0.1167 mL	0.2334 mL

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