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Description:
Daprodustat (GSK1278863) is an orally administered hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor. Phase 2.
Chemical Information:
Molecular Weight (MW) 393.43 Formula
C19H27N3O6
CAS No. 960539-70-2 Solubility (25°C) * DMSO 10 mg/mL warmed (25.41 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
PKCγ PKCβ PKCζ PKCδ PKCα 6 nM 7 nM 60 nM 10 nM 7 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.5417 mL 12.7087 mL 25.4175 mL 5 mM 0.5083 mL 2.5417 mL 5.0835 mL 10 mM 0.2542 mL 1.2709 mL 2.5417 mL 50 mM 0.0508 mL 0.2542 mL 0.5083 mL
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