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Daprodustat (GSK1278863)

Daprodustat (GSK1278863)

Catalog Number: CC8327 Rank: comment rank 5

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$ 102.00
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Description:

Daprodustat (GSK1278863) is an orally administered hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor. Phase 2.

Chemical Information:

Molecular Weight (MW) 393.43
Formula

 

C19H27N3O6

 

CAS No. 960539-70-2
Solubility (25°C) * DMSO 10 mg/mL warmed (25.41 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
PKCγ PKCβ PKCζ PKCδ PKCα
6 nM 7 nM 60 nM 10 nM 7 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5417 mL 12.7087 mL 25.4175 mL
5 mM 0.5083 mL 2.5417 mL 5.0835 mL
10 mM 0.2542 mL 1.2709 mL 2.5417 mL
50 mM 0.0508 mL 0.2542 mL 0.5083 mL


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