Description：

Dacinostat (LAQ824) is a novel HDAC inhibitor with IC50 of 32 nM and is known to activate the p21 promoter.

Chemical Information：

Molecular Weight (MW)		379.459
Formula		C22H25N3O3
CAS No.		404951-53-7
Solubility (25°C) *	DMSO	76 mg/mL (200.28 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

mGluR4 (Human) mGluR4 (Rat ) 240 nM 110 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6353 mL	13.1767 mL	26.3533 mL
5 mM	0.5271 mL	2.6353 mL	5.2707 mL
10 mM	0.2635 mL	1.3177 mL	2.6353 mL
50 mM	0.0527 mL	0.2635 mL	0.5271 mL

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