Description：

Dacarbazine is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis; used in the treatment of various cancers.

Chemical Information：

Molecular Weight (MW)		182.18
Formula		C6H10N6O
CAS No.		4342-03-4
Solubility (25°C) *	DMSO	12 mg/mL warmed (65.86 mM)
	Water	2 mg/mL warmed (10.97 mM)
	Alcohol	1 mg/mL warmed (5.48 mM)

Biological Activity：

Targets IC50

TrkA 2 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	5.4891 mL	27.4454 mL	54.8908 mL
5 mM	1.0978 mL	5.4891 mL	10.9782 mL
10 mM	0.5489 mL	2.7445 mL	5.4891 mL
50 mM	0.1098 mL	0.5489 mL	1.0978 mL

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