Description：

AG-490 (Tyrphostin B42) is an inhibitor of EGFR with IC50 of 0.1 μM in cell-free assays, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src.

Chemical Information：

Molecular Weight (MW)		294.30
Formula		C17H14N2O3
CAS No.		133550-30-8
Solubility (25°C) *	DMSO	58 mg/mL (197.07 mM)
	Water	Insoluble
	Alcohol	6 mg/mL (20.38 mM)

Biological Activity：

Targets IC50

InsR IGF-1R 75 nM 35 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.3979 mL	16.9895 mL	33.9789 mL
5 mM	0.6796 mL	3.3979 mL	6.7958 mL
10 mM	0.3398 mL	1.6989 mL	3.3979 mL
50 mM	0.0680 mL	0.3398 mL	0.6796 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last