Description：

CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively.

Chemical Information：

Molecular Weight (MW)		498.40
Formula		C26H24ClN3O3.HCl
CAS No.		1353859-00-3
Solubility (25°C) *	DMSO	57 mg/mL warmed (114.36 mM)
	Water	89 mg/mL warmed (178.57 mM)
	Alcohol	1 mg/mL warmed (2.0 mM)

Biological Activity：

Targets IC50

mTOR 2-10 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0064 mL	10.0321 mL	20.0642 mL
5 mM	0.4013 mL	2.0064 mL	4.0128 mL
10 mM	0.2006 mL	1.0032 mL	2.0064 mL
50 mM	0.0401 mL	0.2006 mL	0.4013 mL

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