Description：

AG-18 inhibits EGFR with IC50 of 35 μM.

Chemical Information：

Molecular Weight (MW)		186.17
Formula		C10H6N2O2
CAS No.		118409-57-7
Solubility (25°C) *	DMSO	37 mg/mL (198.74 mM)
	Water	Insoluble
	Alcohol	37 mg/mL (198.74 mM)

Biological Activity：

Targets IC50

HDAC6 HDAC2 HDAC10 HDAC1 HDAC3 HDAC8 17 nM (Ki) 19 nM (Ki) 24 nM (Ki) 7 nM (Ki) 8.2 nM (Ki) 280 nM (Ki)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	5.3714 mL	26.8572 mL	53.7143 mL
5 mM	1.0743 mL	5.3714 mL	10.7429 mL
10 mM	0.5371 mL	2.6857 mL	5.3714 mL
50 mM	0.1074 mL	0.5371 mL	1.0743 mL

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