Description：

Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM） and Histone deacetylase; activates Nrf2 pathway and supresses the activation of transcription factor NF-κB.

Chemical Information：

Molecular Weight (MW)		368.38
Formula		C21H20O6
CAS No.		458-37-7
Solubility (25°C) *	DMSO	73 mg/mL (198.16 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

GSK-3β 60 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7146 mL	13.5729 mL	27.1459 mL
5 mM	0.5429 mL	2.7146 mL	5.4292 mL
10 mM	0.2715 mL	1.3573 mL	2.7146 mL
50 mM	0.0543 mL	0.2715 mL	0.5429 mL

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