Description：

CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.

Chemical Information：

Molecular Weight (MW)		434.49
Formula		C24H26N4O4
CAS No.		1012054-59-9
Solubility (25°C) *	DMSO	20 mg/mL (46.03 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

DNA methyltransf 115 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3015 mL	11.5077 mL	23.0155 mL
5 mM	0.4603 mL	2.3015 mL	4.6031 mL
10 mM	0.2302 mL	1.1508 mL	2.3015 mL
50 mM	0.0460 mL	0.2302 mL	0.4603 mL

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