Description：

CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.

Chemical Information：

Molecular Weight (MW)		391.77
Formula		C19H13ClF3N3O
CAS No.		871362-31-1
Solubility (25°C) *	DMSO	78 mg/mL (199.09 mM)
	Water	Insoluble
	Alcohol	10 mg/mL (25.52 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5525 mL	12.7626 mL	25.5252 mL
5 mM	0.5105 mL	2.5525 mL	5.1050 mL
10 mM	0.2553 mL	1.2763 mL	2.5525 mL
50 mM	0.0511 mL	0.2553 mL	0.5105 mL

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