Description：

CPI-613, a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. Phase 2.

Chemical Information：

Molecular Weight (MW)		388.59
Formula		C22H28O2S2
CAS No.		95809-78-2
Solubility (25°C) *	DMSO	77 mg/mL (198.15 mM)
	Water	Insoluble
	Alcohol	77 mg/mL (198.15 mM)

Biological Activity：

Targets IC50

Akt1 Akt2 Akt3 5 nM 18 nM 8 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5734 mL	12.8670 mL	25.7341 mL
5 mM	0.5147 mL	2.5734 mL	5.1468 mL
10 mM	0.2573 mL	1.2867 mL	2.5734 mL
50 mM	0.0515 mL	0.2573 mL	0.5147 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last