Description：

CPI-455 is a specific KDM5 inhibitor, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with standard chemotherapy or targeted agents.

Chemical Information：

Molecular Weight (MW)		314.77
Formula		C16H15ClN4O
CAS No.		1628208-23-0(free base)
Solubility (25°C) *	DMSO	10 mg/mL (31.76 mM)
	Water	Insoluble
	Alcohol	2 mg/mL (6.35 mM)

Biological Activity：

Targets IC50

B-raf B-RafV600E c-Raf 3.2 nM 0.8 nM 5.0 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1769 mL	15.8846 mL	31.7692 mL
5 mM	0.6354 mL	3.1769 mL	6.3538 mL
10 mM	0.3177 mL	1.5885 mL	3.1769 mL
50 mM	0.0635 mL	0.3177 mL	0.6354 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last