Description：

Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with K_d of 0.4 μM.Phase 3.

Chemical Information：

Molecular Weight (MW)		316.35
Formula		C18H20O5
CAS No.		117048-59-6
Solubility (25°C) *	DMSO	63 mg/mL (199.14 mM)
	Water	Insoluble
	Alcohol	34 mg/mL warmed (107.47 mM)

Biological Activity：

Targets IC50

EGFR HER2 23 nM 17 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1611 mL	15.8053 mL	31.6106 mL
5 mM	0.6322 mL	3.1611 mL	6.3221 mL
10 mM	0.3161 mL	1.5805 mL	3.1611 mL
50 mM	0.0632 mL	0.3161 mL	0.6322 mL

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